Search on: TESTIS-BLOOD BARRIER 
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Descriptor English:   Blood-Testis Barrier 
Descriptor Spanish:   Barrera Hematotesticular 
Descriptor Portuguese:   Barreira Hematotesticular 
Synonyms English:   Testis-Blood Barrier  
Tree Number:   A05.360.444.849.700.349
A07.045
Definition English:   A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS. 
Indexing Annotation English:   coord IM with endogenous substance /metab (IM) or exogenous substance /pharmacokin (IM)
See Related English:   Capillary Permeability
 
History Note English:   76(75); was see under TESTIS 1975 
Allowable Qualifiers English:  
AB abnormalities AH anatomy & histology
CH chemistry CY cytology
DE drug effects EM embryology
EN enzymology GD growth & development
IM immunology IN injuries
IR innervation ME metabolism
MI microbiology PS parasitology
PA pathology PH physiology
PP physiopathology RE radiation effects
RA radiography RI radionuclide imaging
SE secretion SU surgery
TR transplantation US ultrasonography
UL ultrastructure VI virology
Record Number:   23171 
Unique Identifier:   D001814 

Occurrence in VHL:
 

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